Tablets from obesity help only serious and responsible people
When in June last year, fat blocker Alli went to the pharmacy, the Americans rushed to buy the first OTC weight loss tool, approved by the Office of the Food and Drug Administration. But soon a Alli found a nasty side effects (inability to control the bowels, if calling a spade a spade), and many of those who took the drug and did not notice any weight loss.
In addition to Alli, now in the U.S. market, six drugs for weight loss prescription. Some, like Alli, block the absorption of fat in the body, while others affect the appetite center in the brain, but the reality is that no matter how many pills you take, they do not work by themselves. «Currently available drugs do not really help, - says Anne Fletcher (Anne Fletcher), a certified nutritionist. - As soon as people stop to take them, many gain weight again ».
Yet pharmaceutical industry and consumers continue to place high expectations on «pills for obesity». Today, several new drugs in the late stages of clinical trials, including experimental medicine lorkazerin, variant fen-dryer, which withdrew from the proceedings due to the fact that it caused heart problems. At least thirty companies developing tools for weight loss, and experts expect that in the next few years the market will be 10-15 new drugs, and the market volume of such drugs in 2016, according to preliminary estimates, will reach $ 2 billion.
Scientists say that in combination with diet and exercise for weight loss drugs can help people lose 5-10% more weight. But because different drugs have different affects on the body, some drugs are better able to help some people, and others - to others. For example, research examining the differences between sibutramine (trade name «Meridia») and orlistat (Xenical and Alli), found that orlistat helps to achieve better results for people who can be called «responsible», «collected», - they closely followed the number of fat, which is received from food. Those who find it difficult to limit yourself to food, more help sibutramine, acting on the hunger center in the brain and causes a feeling of satiety.
In general, those who are taking drugs for slimming, make one big mistake - they think these drugs are a magic tool. «We can not expect that the pill will do everything for you, - says Gary Foster, director of the Center for the Study of Obesity at Temple University, Philadelphia. - Tablets - this is only one leg of a chair. The remaining three - exercise, diet and lifestyle ».
As for side effects, then, firstly, data on the extent of obesity drugs are safe in the long term, especially for young people, no. Secondly, the side effects were observed in all the drugs on the market. Sibutramine can increase blood pressure and heart rate. Orlistat may lead to uncontrolled disorders of the intestine. Rimonabant, which is awaiting authorization to release for sale in America, but is already sold in Europe, can cause nausea, anxiety, depression and insomnia. And yet for people suffering from obesity, the dignity of these drugs may outweigh the risks.
«The best result of such tablets bring people who are ready to get serious about losing weight and are willing to take responsibility for their decisions and their actions», - said Pat Baird (Pat Baird), dietitian and nutrition consultant for the company GlaxoSmithKline, which is responsible for communication with consumers, host Alli. On the day she advises to 25 people, responding to questions about weight loss, weight loss programs and medications. Baird notes that for some people to help you lose weight even side effects of Alli - if a person eats more than the allowed 15 grams of fat in one meal, he may face unpleasant consequences in the form of intestinal disorders.
When in June last year, fat blocker Alli went to the pharmacy, the Americans rushed to buy the first OTC weight loss tool, approved by the Office of the Food and Drug Administration. But soon a Alli found a nasty side effects (inability to control the bowels, if calling a spade a spade), and many of those who took the drug and did not notice any weight loss.
In addition to Alli, now in the U.S. market, six drugs for weight loss prescription. Some, like Alli, block the absorption of fat in the body, while others affect the appetite center in the brain, but the reality is that no matter how many pills you take, they do not work by themselves. «Currently available drugs do not really help, - says Anne Fletcher (Anne Fletcher), a certified nutritionist. - As soon as people stop to take them, many gain weight again ».
Yet pharmaceutical industry and consumers continue to place high expectations on «pills for obesity». Today, several new drugs in the late stages of clinical trials, including experimental medicine lorkazerin, variant fen-dryer, which withdrew from the proceedings due to the fact that it caused heart problems. At least thirty companies developing tools for weight loss, and experts expect that in the next few years the market will be 10-15 new drugs, and the market volume of such drugs in 2016, according to preliminary estimates, will reach $ 2 billion.
Scientists say that in combination with diet and exercise for weight loss drugs can help people lose 5-10% more weight. But because different drugs have different affects on the body, some drugs are better able to help some people, and others - to others. For example, research examining the differences between sibutramine (trade name «Meridia») and orlistat (Xenical and Alli), found that orlistat helps to achieve better results for people who can be called «responsible», «collected», - they closely followed the number of fat, which is received from food. Those who find it difficult to limit yourself to food, more help sibutramine, acting on the hunger center in the brain and causes a feeling of satiety.
In general, those who are taking drugs for slimming, make one big mistake - they think these drugs are a magic tool. «We can not expect that the pill will do everything for you, - says Gary Foster, director of the Center for the Study of Obesity at Temple University, Philadelphia. - Tablets - this is only one leg of a chair. The remaining three - exercise, diet and lifestyle ».
As for side effects, then, firstly, data on the extent of obesity drugs are safe in the long term, especially for young people, no. Secondly, the side effects were observed in all the drugs on the market. Sibutramine can increase blood pressure and heart rate. Orlistat may lead to uncontrolled disorders of the intestine. Rimonabant, which is awaiting authorization to release for sale in America, but is already sold in Europe, can cause nausea, anxiety, depression and insomnia. And yet for people suffering from obesity, the dignity of these drugs may outweigh the risks.
«The best result of such tablets bring people who are ready to get serious about losing weight and are willing to take responsibility for their decisions and their actions», - said Pat Baird (Pat Baird), dietitian and nutrition consultant for the company GlaxoSmithKline, which is responsible for communication with consumers, host Alli. On the day she advises to 25 people, responding to questions about weight loss, weight loss programs and medications. Baird notes that for some people to help you lose weight even side effects of Alli - if a person eats more than the allowed 15 grams of fat in one meal, he may face unpleasant consequences in the form of intestinal disorders.
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